Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.40 |
| ▸ | FNTB | P49356 | 6/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809054 | 1.00 | FNTA (0.40) | FNTAFNTBPGGT1BMMEANPEP | |
| SCHEMBL9809021 | 0.84 | LTA4H (0.45) | FNTAFNTBPGGT1BMMEANPEP | |
| SCHEMBL9808978 | 0.82 | CYP1A2 (0.51) | MMEANPEPLTA4HSLC1A3SLC1A2 | |
| SCHEMBL9808993 | 0.82 | CYP1A2 (0.51) | MMEANPEPLTA4HSLC1A3SLC1A2 | |
| SCHEMBL9808968 | 0.82 | CYP1A2 (0.51) | MMEANPEPLTA4HSLC1A3SLC1A2 | |
| SCHEMBL9808980 | 0.75 | SLC1A3 (0.37) | MMEANPEPSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9808994 | 0.75 | SLC1A3 (0.37) | MMEANPEPSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7318233 | 0.69 | MME (0.56) | FNTAFNTBPGGT1BMMEANPEP | |
| SCHEMBL7440318 | 0.68 | LTA4H (0.66) | FNTAFNTBPGGT1BMMEANPEP | |
| SCHEMBL7440316 | 0.68 | LTA4H (0.66) | FNTAFNTBPGGT1BMMEANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322633-B1 | MERCAPTO-ACYLAMINO ACID ANTIHYPERTENSIVES | SCHERING CORPORATION (US) | 1991-05-22 | — | — | EP | claimed |
| EP-0390839-A1 | MERCAPTO-ACYLAMINO ACID ANTIHYPERTENSIVES | SCHERING CORPORATION (US) | 1990-10-10 | — | — | EP | claimed |
| EP-0322633-A1 | Mercapto-acylamino acid antihypertensives | SCHERING CORPORATION (US) | 1989-07-05 | — | — | EP | claimed |
| WO-1989005796-A1 | MERCAPTO-ACYLAMINO ACID ANTIHYPERTENSIVES | SCHERING CORPORATION (US) | 1989-06-29 | — | — | WO | claimed |
| EP-0322633-B1 | MERCAPTO-ACYLAMINO ACID ANTIHYPERTENSIVES | SCHERING CORPORATION (US) | 1991-05-22 | — | — | EP | disclosed |
| EP-0390839-A1 | MERCAPTO-ACYLAMINO ACID ANTIHYPERTENSIVES | SCHERING CORPORATION (US) | 1990-10-10 | — | — | EP | disclosed |
| EP-0322633-A1 | Mercapto-acylamino acid antihypertensives | SCHERING CORPORATION (US) | 1989-07-05 | — | — | EP | disclosed |
| WO-1989005796-A1 | MERCAPTO-ACYLAMINO ACID ANTIHYPERTENSIVES | SCHERING CORPORATION (US) | 1989-06-29 | — | — | WO | disclosed |