SCHEMBL12379211

SCHEMBL12379211

CC(C)c1cccoc1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.45
CA1 P00915 2/20 0.41
CA9 Q16790 1/20 0.41
GABRA1 P14867 3/20 0.39
FAAH O00519 2/20 0.39
GABRB2 P47870 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
HPGD P15428 2/20 0.39
CA2 P00918 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
GABRB1 P18505 1/20 0.39
PTGS1 P23219 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2C P28335 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7482429 0.72 CYP2C9 (0.44) MAPTCA1CA9HPGDLMNA
SCHEMBL346071 0.72 CA1 (0.41) MAPTCA1CA9HPGDLMNA
SCHEMBL14627844 0.71 KDM4E (0.52) MAPTCA1CA9GABRA1FAAH
SCHEMBL13150866 0.71 KDM4E (0.38) MAPTCA1CA9GABRA1FAAH
SCHEMBL17530314 0.70
SCHEMBL11877385 0.70 KMT2A (0.41) MAPTCA1CA9HPGDLMNA
SCHEMBL14602504 0.70 MAPT (0.42) MAPTCA1CA9GABRA1FAAH
SCHEMBL980904 0.69
SCHEMBL30458138 0.68 GABRA1 (0.45) MAPTCA1CA9GABRA1GABRB2
SCHEMBL80874 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109722405-B Recombinant escherichia coli for producing isopropyl pyrone by utilizing glucose and application 创享(天津)生物科技发展有限公司 2023-06-23 CN claimed
CN-109722405-B Recombinant escherichia coli for producing isopropyl pyrone by utilizing glucose and application 创享(天津)生物科技发展有限公司 2023-06-23 CN disclosed
CN-109722405-B Recombinant escherichia coli for producing isopropyl pyrone by utilizing glucose and application 创享(天津)生物科技发展有限公司 2023-06-23 CN disclosed
CN-109722405-B Recombinant escherichia coli for producing isopropyl pyrone by utilizing glucose and application 创享(天津)生物科技发展有限公司 2023-06-23 CN disclosed
US-7989430-B2 Antibacterial agents REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2011-08-02 US disclosed
US-7989430-B2 Antibacterial agents REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2011-08-02 US disclosed
CN-100532556-C Coded vitamin B6Gene of phosphate phosphatase and use thereof DSM IP ASSETS BV (NL) 2009-08-26 CN disclosed
US-20080293666-A1 Antibacterial Agents REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2008-11-27 US disclosed
CN-1685044-A A gene encoding vitamin B 6 phosphate phosphatase and use thereof DSM IP ASSETS BV (NL) 2005-10-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293666-A1 Antibacterial Agents MRPL21, ABCB7, MSR1 MAPT 4800/4885CA1 4489/4885CA9 2674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.