Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809067 | 0.89 | CYP19A1 (0.42) | CYP19A1POLBMAOAMAOBMEN1 | |
| SCHEMBL3882745 | 0.82 | CYP19A1 (0.56) | CYP19A1POLBMAOAMAOBMEN1 | |
| SCHEMBL536896 | 0.81 | CYP19A1 (0.55) | CYP19A1POLBMAOAMAOBMEN1 | |
| SCHEMBL9809117 | 0.76 | CYP19A1 (0.45) | CYP19A1POLBMAOAMAOBMEN1 | |
| SCHEMBL17035227 | 0.75 | BCHE (0.64) | POLBMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL9809061 | 0.74 | MGLL (0.37) | POLBKMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9809118 | 0.73 | POLB (0.42) | POLBMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL198057 | 0.72 | ABCB1 (0.50) | POLBMAOAMAOBALDH1A1ALOX15 | |
| SCHEMBL9809063 | 0.72 | BCHE (0.49) | CYP19A1POLBMAOAMAOBMEN1 | |
| SCHEMBL23403198 | 0.72 | TSHR (0.45) | POLBMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |