Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329930 | 0.92 | KDM4E (0.53) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL31546073 | 0.81 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL14077386 | 0.80 | CYP2A6 (0.43) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL2536582 | 0.79 | TAAR1 (0.40) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL14854495 | 0.78 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL9911677 | 0.78 | KDM4E (0.35) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL10452473 | 0.77 | NPC1 (0.54) | SLC6A4SLC6A2SLC6A3KDM4E | |
| SCHEMBL10300821 | 0.77 | TSHR (0.54) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL5852687 | 0.77 | TSHR (0.54) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL29434698 | 0.77 | TSHR (0.54) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031566-B2 | PHOTOSENSITIVE NEGATIVE-WORKING TONABLE ELEMENT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-29 | — | — | EP | disclosed |
| EP-0031566-B1 | PHOTOSENSITIVE NEGATIVE-WORKING TONABLE ELEMENT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-14 | — | — | EP | disclosed |
| US-4356252-A | POLYMERIC BINDER, PHOTOINITIATOR, ACETAL, PLASTICIZING, POLYMERIC ANHYDRIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-10-26 | — | — | US | disclosed |
| US-4294909-A | Photosensitive negative-working toning process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-10-13 | — | — | US | disclosed |
| US-4292394-A | Process for preparing multicolor toned images on a single photosensitive layer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-09-29 | — | — | US | disclosed |
| EP-0031566-A1 | Photosensitive negative-working tonable element | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-07-08 | — | — | EP | disclosed |