Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL6399334 | 0.96 | TSHR (0.67) | — | |
| Monoethanolamine SCHEMBL29019843 | 0.83 | — | — | |
| Monoethanolamine SCHEMBL21753520 | 0.83 | — | — | |
| Monoethanolamine SCHEMBL4820833 | 0.83 | TSHR (0.89) | — | |
| Monoethanolamine SCHEMBL333552 | 0.83 | — | — | |
| Monoethanolamine SCHEMBL28491845 | 0.83 | — | — | |
| Monoethanolamine SCHEMBL26645800 | 0.83 | — | — | |
| Monoethanolamine SCHEMBL5985807 | 0.79 | — | — | |
| Monoethanolamine SCHEMBL29152311 | 0.79 | TSHR (0.80) | — | |
| Monoethanolamine SCHEMBL11769334 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167310-B1 | PLATINUM CO-ORDINATION COMPOUNDS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1991-05-29 | — | — | EP | disclosed |
| US-4956454-A | AMINE LIGANDS BONDED TO PLATINUM AND MONOCLONAL ANTIBODIES TO FORM COORDINATION COMPOUNDS | JOHNSON MATTHEY PLC (GB) | 1990-09-11 | — | — | US | disclosed |
| US-4760155-A | Platinum co-ordination compounds | JOHNSON MATTHEY PLC (GB) | 1988-07-26 | — | — | US | disclosed |
| EP-0167310-A2 | Platinum co-ordination compounds | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1986-01-08 | — | — | EP | disclosed |