Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoquinoline SCHEMBL972906 | 0.90 | TNF (0.42) | TNFLMNAKDM4ECYP1A2CYP3A4 | |
| Isoquinoline SCHEMBL11573107 | 0.89 | TNF (0.44) | TNFLMNAKDM4ECYP1A2CYP3A4 | |
| Isoquinoline SCHEMBL31588723 | 0.88 | TNF (0.48) | TNFLMNAKDM4ECYP1A2CYP3A4 | |
| Isoquinoline SCHEMBL1536317 | 0.88 | TNF (0.48) | TNFLMNAKDM4ECYP1A2CYP3A4 | |
| Isoquinoline SCHEMBL29355164 | 0.88 | TNF (0.48) | TNFLMNAKDM4ECYP1A2CYP3A4 | |
| Isoquinoline SCHEMBL9654 | 0.88 | TNF (0.48) | TNFLMNAKDM4ECYP1A2CYP3A4 | |
| Naphthalene SCHEMBL7327012 | 0.88 | TNF (0.48) | TNFLMNAKDM4ECYP1A2CYP3A4 | |
| Isoquinoline SCHEMBL30286035 | 0.88 | TNF (0.48) | TNFLMNAKDM4ECYP1A2CYP3A4 | |
| Isoquinoline SCHEMBL6612840 | 0.86 | CYP1A2 (0.48) | TNFLMNAKDM4ECYP1A2CYP3A4 | |
| Isoquinoline SCHEMBL2311387 | 0.86 | CYP1A2 (0.48) | TNFLMNAKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224207-B1 | CHARGE TRANSFER COMPLEX | THE JAPAN CARLIT CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |
| US-4688153-A | ELECTROLYTIC CAPACITORS | THE JAPAN CARLIT CO., LTD. (JP) | 1987-08-18 | — | — | US | disclosed |
| EP-0224207-A2 | Charge transfer complex | THE JAPAN CARLIT CO., LTD. (JP) | 1987-06-03 | — | — | EP | disclosed |