Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | HRH1 | P35367 | 4/20 | 0.64 |
| ▸ | HRH2 | P25021 | 3/20 | 0.64 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809235 | 0.91 | HRH1 (0.63) | USP2ALDH1A1HPGDHRH1HRH2 | |
| SCHEMBL9809294 | 0.91 | HRH1 (0.64) | USP2ALDH1A1HPGDHRH1HRH2 | |
| SCHEMBL9809418 | 0.90 | HRH3 (0.64) | USP2ALDH1A1HPGDHRH1HRH2 | |
| SCHEMBL12359053 | 0.89 | USP2 (0.91) | USP2ALDH1A1HPGDHRH1CXCR1 | |
| SCHEMBL9809405 | 0.88 | HRH3 (0.61) | USP2ALDH1A1HPGDHRH1HRH2 | |
| SCHEMBL9809336 | 0.87 | HRH1 (0.66) | USP2ALDH1A1HPGDHRH1HRH2 | |
| SCHEMBL9809346 | 0.86 | HRH1 (0.57) | USP2ALDH1A1HPGDHRH1HRH2 | |
| SCHEMBL9809297 | 0.84 | HRH1 (0.63) | USP2ALDH1A1HPGDHRH1HRH2 | |
| SCHEMBL9809265 | 0.83 | HRH1 (0.63) | USP2ALDH1A1HPGDHRH1HRH2 | |
| SCHEMBL9809231 | 0.83 | HRH1 (0.63) | USP2ALDH1A1HPGDHRH1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211928-B1 | PIPERAZINECARBOXAMIDES HAVING A PHENOXYALKYL OR THIOPHENOXYALKYL SIDE CHAIN | AB LEO (SE) | 1991-05-02 | — | — | EP | disclosed |
| US-4778789-A | PSYCHOLOGICAL DISORDERS | AKTIEBOLAGET LEO (SE) | 1988-10-18 | — | — | US | disclosed |
| EP-0211928-A1 | PIPERAZINECARBOXAMIDES HAVING A PHENOXYALKYL OR THIOPHENOXYALKYL SIDE CHAIN. | LEO AB (SE) | 1987-03-04 | — | — | EP | disclosed |
| WO-1986004584-A1 | NOVEL PIPERAZINECARBOXAMIDES HAVING A PHENOXYALKYL OR THIOPHENOXYALKYL SIDE CHAIN | AKTIEBOLAGET LEO (SE) | 1986-08-14 | — | — | WO | disclosed |