Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HRH2 | P25021 | 3/20 | 0.53 |
| ▸ | HRH1 | P35367 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9809255 | 0.96 | HRH3 (0.55) | HTR2AHRH3EPHX2ALDH1A1POLB | |
| SCHEMBL9809250 | 0.94 | HRH1 (0.59) | HTR2AHRH3ALDH1A1HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL9809406 | 0.93 | HRH1 (0.58) | HTR2AHRH3ALDH1A1HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL10933981 | 0.82 | POLB (0.54) | HTR2AALDH1A1POLBHRH2HRH1 | |
| SCHEMBL3581520 | 0.81 | HRH3 (0.62) | HRH3EPHX2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL10507603 | 0.81 | TSHR (0.60) | HRH3ALDH1A1POLB | |
| SCHEMBL9809265 | 0.81 | HRH1 (0.63) | HTR2AHRH3ALDH1A1HRH2HRH1 | |
| SCHEMBL9809351 | 0.81 | HRH2 (0.69) | HTR2AHRH3ALDH1A1HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL8021274 | 0.81 | LMNA (0.54) | ALDH1A1POLB | |
| SCHEMBL10509677 | 0.81 | POLB (0.57) | HRH3EPHX2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211928-B1 | PIPERAZINECARBOXAMIDES HAVING A PHENOXYALKYL OR THIOPHENOXYALKYL SIDE CHAIN | AB LEO (SE) | 1991-05-02 | — | — | EP | disclosed |