Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26278001 | 0.98 | THRA (0.46) | THRATHRBNR5A1GPR84LPAR3 | |
| SCHEMBL6658770 | 0.98 | THRA (0.46) | THRATHRBNR5A1GPR84LPAR3 | |
| SCHEMBL9809623 | 0.98 | THRA (0.46) | THRATHRBNR5A1GPR84LPAR3 | |
| SCHEMBL26278000 | 0.98 | THRA (0.46) | THRATHRBNR5A1GPR84LPAR3 | |
| SCHEMBL9809630 | 0.98 | THRA (0.46) | THRATHRBNR5A1GPR84LPAR3 | |
| SCHEMBL9809613 | 0.98 | THRA (0.46) | THRATHRBNR5A1GPR84LPAR3 | |
| Squaric Acid Dibutyl Ester SCHEMBL56180 | 0.92 | CYP3A4 (0.44) | THRATHRBNR5A1TP53TSHR | |
| SCHEMBL2550628 | 0.85 | NR5A1 (0.44) | THRATHRBNR5A1GPR84LPAR3 | |
| SCHEMBL4140379 | 0.84 | NR5A1 (0.48) | THRATHRBNR5A1GPR84LPAR3 | |
| SCHEMBL5571442 | 0.83 | NR5A1 (0.47) | THRATHRBNR5A1GPR84LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585895-A | Processes for the preparation of mixed squaraine compositions | XEROX CORPORATION (US) | 1986-04-29 | — | — | US | claimed |
| US-4525592-A | Process for squaraine compositions | XEROX CORPORATION (US) | 1985-06-25 | — | — | US | claimed |
| US-4092146-A | POSTEMERGENCE HERBICIDES, PLANT GROWTH INHIBITORS, DESSICANTS, ETHERS OF CYCLOBUTENEDIONE | CIBA-GEIGY CORPORATION (US) | 1978-05-30 | — | — | US | claimed |
| JP-3206068-A | — | — | None | — | — | JP | disclosed |
| JP-H03206068-A | CYCLOBUTENE-1,2-DIONE DERIVATIVE | IKEDA MOHANDOU:KK | 1991-09-09 | — | — | JP | disclosed |
| EP-0145400-B1 | PHOTOCONDUCTIVE DEVICES CONTAINING NOVEL SQUARAINE COMPOUNDS | XEROX CORPORATION (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4746756-A | Photoconductive imaging members with novel fluorinated squaraine compounds | XEROX CORPORATION (US) | 1988-05-24 | — | — | US | disclosed |
| US-4621038-A | Photoconductive imaging members with novel symmetrical fluorinated squaraine compounds | XEROX CORPORATION (US) | 1986-11-04 | — | — | US | disclosed |
| US-4585895-A | Processes for the preparation of mixed squaraine compositions | XEROX CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |
| US-4525592-A | Process for squaraine compositions | XEROX CORPORATION (US) | 1985-06-25 | — | — | US | disclosed |
| EP-0145400-A2 | Photoconductive devices containing novel squaraine compounds | XEROX CORPORATION (US) | 1985-06-19 | — | — | EP | disclosed |
| US-4486520-A | Photoconductive devices containing novel squaraine compositions | XEROX CORPORATION (US) | 1984-12-04 | — | — | US | disclosed |