Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorobenzene SCHEMBL7446152 | 0.97 | TSHR (0.43) | TSHRNFE2L2ACHEKCNN4TAAR1 | |
| Fluorobenzene SCHEMBL28787954 | 0.88 | NFE2L2 (0.46) | TSHRNFE2L2ACHENPC1RAB9A | |
| Fluorobenzene SCHEMBL27733550 | 0.86 | — | — | |
| Fluorobenzene SCHEMBL28081726 | 0.86 | — | — | |
| Fluorobenzene SCHEMBL14012524 | 0.86 | — | — | |
| SCHEMBL22526495 | 0.86 | NFE2L2 (0.53) | TSHRNFE2L2ACHEKCNN4BBOX1 | |
| Fluorobenzene SCHEMBL15544432 | 0.86 | NFE2L2 (0.53) | TSHRNFE2L2ACHEKCNN4BBOX1 | |
| Fluorobenzene SCHEMBL12363 | 0.86 | — | — | |
| Fluorobenzene SCHEMBL7024891 | 0.86 | — | — | |
| Fluorobenzene SCHEMBL27957654 | 0.86 | NFE2L2 (0.53) | TSHRNFE2L2ACHEKCNN4BBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1950334-A | Ortho substituted aryl or heteroaryl amide compounds | PFIZER (US) | 2007-04-18 | — | — | CN | disclosed |
| CN-1396895-A | Method for producing 2,3,5,6-tetrahalogen-xylylidene compounds | BAYER AG (DE) | 2003-02-12 | — | — | CN | disclosed |
| EP-0145400-B1 | PHOTOCONDUCTIVE DEVICES CONTAINING NOVEL SQUARAINE COMPOUNDS | XEROX CORPORATION (US) | 1991-05-29 | — | — | EP | disclosed |
| EP-0144206-B1 | PROCESS FOR SYNTHESISING SQUARAINE COMPOSITIONS | XEROX CORPORATION (US) | 1989-04-19 | — | — | EP | disclosed |
| EP-0146301-B1 | PROCESS FOR SYNTHESIZING SQUARAINE COMPOSITIONS | XEROX CORPORATION (US) | 1988-07-13 | — | — | EP | disclosed |
| US-4606986-A | Electrophotographic elements containing unsymmetrical squaraines | XEROX CORPORATION (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0146301-A1 | Process for synthesizing squaraine compositions | XEROX CORPORATION (US) | 1985-06-26 | — | — | EP | disclosed |
| EP-0145400-A2 | Photoconductive devices containing novel squaraine compounds | XEROX CORPORATION (US) | 1985-06-19 | — | — | EP | disclosed |
| EP-0144206-A2 | Process for synthesising squaraine compositions | XEROX CORPORATION (US) | 1985-06-12 | — | — | EP | disclosed |
| US-4523035-A | BLUE AND GREEN PIGMENTS | XEROX CORPORATION (US) | 1985-06-11 | — | — | US | disclosed |
| US-4521621-A | Novel squarine systems | XEROX CORPORATION (US) | 1985-06-04 | — | — | US | disclosed |
| US-4486520-A | Photoconductive devices containing novel squaraine compositions | XEROX CORPORATION (US) | 1984-12-04 | — | — | US | disclosed |