Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ELANE | P08246 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | ACACA | Q13085 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487192 | 0.98 | HSD17B10 (0.59) | HSD17B10LMNAGAAELANEMAPT | |
| Hydrogen Peroxide SCHEMBL9578945 | 0.94 | LMNA (0.57) | HSD17B10LMNAGAAELANEMAPT | |
| SCHEMBL1714626 | 0.92 | LMNA (0.59) | HSD17B10LMNAGAAELANEMAPT | |
| SCHEMBL8757336 | 0.91 | SMN1; SMN2 (0.50) | HSD17B10LMNAGAAMAPTSMN1; SMN2 | |
| SCHEMBL11791125 | 0.90 | LMNA (0.57) | HSD17B10LMNAGAAELANEMAPT | |
| SCHEMBL14839083 | 0.85 | ELANE (0.59) | HSD17B10LMNAELANEMAPTSMN1; SMN2 | |
| SCHEMBL10781479 | 0.85 | HSD17B10 (0.58) | HSD17B10LMNAGAAELANEMAPT | |
| SCHEMBL237465 | 0.85 | SMN1; SMN2 (0.51) | HSD17B10LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5699582 | 0.84 | SMN1; SMN2 (0.54) | LMNAELANEMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9158246 | 0.84 | HSD17B10 (0.76) | HSD17B10LMNAGAAELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983777-A | Diisopropylbiphenyl mono- and di-hydroperoxides, process for the preparation thereof, and compounds derived therefrom | EASTMAN KODAK COMPANY (US) | 1991-01-08 | — | — | US | disclosed |