Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADH1B | P00325 | 2/20 | 0.31 |
| ▸ | ADH1A | P07327 | 2/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1300385 | 0.74 | — | — | |
| SCHEMBL1598821 | 0.72 | — | — | |
| SCHEMBL21549670 | 0.71 | LMNA (0.42) | LMNAADH1BADH1AADH7ADH1C | |
| SCHEMBL20081502 | 0.71 | LMNA (0.36) | LMNA | |
| SCHEMBL1270193 | 0.71 | — | — | |
| SCHEMBL24285705 | 0.70 | LMNA (0.41) | LMNAADH1BADH1AADH7ADH1C | |
| SCHEMBL12967757 | 0.69 | — | — | |
| SCHEMBL12801638 | 0.69 | — | — | |
| SCHEMBL14495524 | 0.69 | MGAM (0.38) | LMNA | |
| SCHEMBL8433354 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284461-B1 | DERIVATIVES OF GLUTAMIC ACID, THEIR SALTS, PROCESS FOR THEIR PREPARATION, USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1991-06-12 | — | — | EP | disclosed |
| EP-0284461-A1 | Derivatives of glutamic acid, their salts, process for their preparation, use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1988-09-28 | — | — | EP | disclosed |