SCHEMBL9810342

SCHEMBL9810342

CCCCCCC(C)OC(=O)C1=CCC(c2ccc([C@H]3CC[C@H](CCC)CC3)cc2)CC1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.43
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.42
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
MAPK1 P28482 1/20 0.37
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
FAAH O00519 3/20 0.33
PTGER4 P35408 1/20 0.33
PTGER3 P43115 1/20 0.33
PTGER2 P43116 1/20 0.33
NAAA Q02083 1/20 0.32
SPHK1 Q9NYA1 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9810344 1.00 CYP2C9 (0.43) CYP2C9ALDH1A1MAPTLMNAKMT2A
SCHEMBL9810559 0.97 CYP2C9 (0.41) CYP2C9ALDH1A1MAPTLMNAKMT2A
SCHEMBL9810552 0.97 CYP2C9 (0.41) CYP2C9ALDH1A1MAPTLMNAKMT2A
SCHEMBL9810381 0.87 ALDH1A1 (0.43) ALDH1A1MAPTKMT2AKDM4EL3MBTL1
SCHEMBL9810278 0.87 CYP2C9 (0.49) CYP2C9ALDH1A1MAPTLMNAKMT2A
SCHEMBL9810282 0.87 CYP2C9 (0.49) CYP2C9ALDH1A1MAPTLMNAKMT2A
SCHEMBL9810453 0.86 SPHK1 (0.43) ALDH1A1SPHK1
SCHEMBL9810593 0.84 CYP2C9 (0.46) CYP2C9ALDH1A1MAPTLMNAKMT2A
SCHEMBL9810628 0.84 CYP2C9 (0.46) CYP2C9ALDH1A1MAPTLMNAKMT2A
SCHEMBL9810281 0.84 CYP2C9 (0.46) CYP2C9ALDH1A1MAPTLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5068389-A TERTIARY ALCOHOLS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-11-26 US disclosed