Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810269 | 0.99 | PPARG (0.41) | OPRL1OPRM1OPRD1OPRK1PPARG | |
| SCHEMBL9810417 | 0.99 | PPARG (0.41) | OPRL1OPRM1OPRD1OPRK1PPARG | |
| SCHEMBL9810321 | 0.99 | PPARG (0.41) | OPRL1OPRM1OPRD1OPRK1PPARG | |
| SCHEMBL9810669 | 0.96 | OPRL1 (0.41) | OPRL1OPRM1OPRD1OPRK1THRA | |
| SCHEMBL9810460 | 0.95 | THRA (0.42) | OPRL1PPARGTHRATHRBS1PR5 | |
| SCHEMBL9810615 | 0.95 | OPRL1 (0.44) | OPRL1PPARGTHRATHRBS1PR5 | |
| SCHEMBL9810279 | 0.94 | OPRL1 (0.43) | OPRL1PPARGTHRATHRBS1PR5 | |
| SCHEMBL9810515 | 0.94 | THRA (0.43) | OPRL1PPARGTHRATHRBS1PR5 | |
| SCHEMBL9810284 | 0.94 | THRA (0.43) | OPRL1PPARGTHRATHRBS1PR5 | |
| SCHEMBL9810336 | 0.94 | THRA (0.43) | OPRL1PPARGTHRATHRBS1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068389-A | TERTIARY ALCOHOLS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |