Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810598 | 0.83 | MEN1 (0.44) | MEN1NPC1RAB9AKMT2APOLB | |
| SCHEMBL9810413 | 0.83 | MEN1 (0.44) | MEN1NPC1RAB9AKMT2APOLB | |
| SCHEMBL24548567 | 0.80 | GRIN2D (0.44) | MEN1NPC1RAB9AKMT2APOLB | |
| SCHEMBL24520256 | 0.80 | GRIN2D (0.44) | MEN1NPC1RAB9AKMT2APOLB | |
| SCHEMBL24520252 | 0.80 | GRIN2D (0.44) | MEN1NPC1RAB9AKMT2APOLB | |
| SCHEMBL9810409 | 0.80 | GRIN2D (0.44) | MEN1NPC1RAB9AKMT2APOLB | |
| SCHEMBL11603644 | 0.79 | MEN1 (0.41) | MEN1NPC1RAB9AKMT2APOLB | |
| SCHEMBL22552897 | 0.75 | MEN1 (0.38) | MEN1NPC1RAB9AKMT2APOLB | |
| SCHEMBL22552896 | 0.75 | MEN1 (0.38) | MEN1NPC1RAB9AKMT2APOLB | |
| SCHEMBL22552663 | 0.75 | MEN1 (0.38) | MEN1NPC1RAB9AKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284084-B1 | INTENSELY SWEET L-ASPARTYL-3-(BICYCLOALKYL)-L-ALANINE ALKYL ESTERS | THE COCA-COLA COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |
| US-4788069-A | SWEETENING EDIBLE FOODS AND BEVERAGES | THE COCA-COLA COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
| WO-1988007522-A1 | INTENSELY SWEET L-ASPARTYL-3-(BICYCLOALKYL)-L-ALANINE ALKYL ESTERS | THE COCA-COLA COMPANY (US) | 1988-10-06 | — | — | WO | disclosed |
| EP-0284084-A2 | Intensely sweet L-aspartyl-3-(Bicycloalkyl)-L-alanine alkyl esters | THE COCA-COLA COMPANY (US) | 1988-09-28 | — | — | EP | disclosed |