Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.51 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | ATG7 | O95352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAPDH | P04406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810594 | 1.00 | ADORA3 (0.61) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL5983148 | 0.88 | HIF1A (0.51) | ADORA3ADORA2ARXFP1HIF1ALMNA | |
| SCHEMBL5983156 | 0.88 | HIF1A (0.51) | ADORA3ADORA2ARXFP1HIF1ALMNA | |
| SCHEMBL19121006 | 0.86 | ADORA3 (0.64) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL13479946 | 0.86 | ADORA3 (0.64) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL5982465 | 0.85 | ADORA3 (0.67) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL5982454 | 0.85 | ADORA3 (0.67) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL658005 | 0.85 | ADORA3 (0.67) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL658006 | 0.85 | ADORA3 (0.67) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL23215196 | 0.85 | ADORA3 (0.67) | ADORA3ADORA2AHSPA5HSPA8RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013829-A | Stable congener of 2',3'-dideoxyadenosine | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1991-05-07 | — | — | US | disclosed |