Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ACACB | O00763 | 4/20 | 0.44 |
| ▸ | ACACA | Q13085 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810449 | 0.96 | MEN1 (0.46) | TSHRACACBACACAALDH1A1HSP90AA1 | |
| SCHEMBL9810626 | 0.96 | TSHR (0.50) | TSHRALDH1A1HSP90AA1MEN1KMT2A | |
| SCHEMBL9810426 | 0.95 | TSHR (0.45) | TSHRACACBACACAALDH1A1HSP90AA1 | |
| SCHEMBL9810362 | 0.94 | RARB (0.46) | TSHRALDH1A1HSP90AA1MEN1KMT2A | |
| SCHEMBL9810243 | 0.94 | ALDH1A1 (0.48) | TSHRACACBACACAALDH1A1HSP90AA1 | |
| SCHEMBL9810474 | 0.94 | KMT2A (0.43) | TSHRACACBACACAALDH1A1HSP90AA1 | |
| SCHEMBL9810283 | 0.93 | RARB (0.45) | TSHRACACBACACAALDH1A1HSP90AA1 | |
| SCHEMBL9810317 | 0.93 | RARB (0.48) | TSHRALDH1A1HSP90AA1MEN1KMT2A | |
| SCHEMBL9810319 | 0.93 | RARB (0.48) | TSHRALDH1A1HSP90AA1MEN1KMT2A | |
| SCHEMBL9810473 | 0.93 | RARB (0.48) | TSHRALDH1A1HSP90AA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068389-A | TERTIARY ALCOHOLS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |