SCHEMBL9810752

SCHEMBL9810752

CC(=O)Nc1ccc(SCCCCCCOC(C)=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.58
NPC1 O15118 2/20 0.58
GAA P10253 1/20 0.54
PTGS2 P35354 1/20 0.51
HPGD P15428 1/20 0.49
RECQL P46063 1/20 0.49
USP2 O75604 1/20 0.47
LMNA P02545 3/20 0.44
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
POLB P06746 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
HTT P42858 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP1A2 P05177 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CLK1 P49759 1/20 0.42
GFER P55789 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18782334 0.82 RAB9A (0.63) RAB9ANPC1GAAHPGDRECQL
SCHEMBL11385176 0.82 RAB9A (0.63) RAB9ANPC1GAAUSP2LMNA
SCHEMBL9518238 0.81 GAA (0.71) RAB9ANPC1GAAHPGDUSP2
SCHEMBL9478153 0.81 RAB9A (0.62) RAB9ANPC1GAAUSP2LMNA
SCHEMBL8795161 0.81 RAB9A (0.62) RAB9ANPC1GAAUSP2LMNA
SCHEMBL464521 0.80 RAB9A (0.65) RAB9ANPC1GAAHPGDRECQL
SCHEMBL11388934 0.80 RAB9A (0.65) RAB9ANPC1GAAUSP2LMNA
SCHEMBL414342 0.79 RAB9A (0.72) RAB9ANPC1GAAUSP2LMNA
SCHEMBL11662106 0.79 HDAC3 (0.54) RAB9APTGS2LMNAALDH1A1MEN1
SCHEMBL10995756 0.79 RAB9A (0.56) RAB9ANPC1GAAHPGDUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075043-A Liquid crystals EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0370922-A2 An optical article containing a linear condensation polymer exhibiting a high level of second order polarization susceptibility EASTMAN KODAK COMPANY (US) 1990-05-30 EP disclosed