Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299793 | 0.80 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3HTR2AADRB2 | |
| SCHEMBL9057558 | 0.80 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3HTR2AADRB2 | |
| SCHEMBL9973633 | 0.80 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3HTR2AADRB2 | |
| Hydrochloric Acid SCHEMBL9055032 | 0.78 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3HTR2AADRB2 | |
| SCHEMBL7352304 | 0.77 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3HTR2AADRB2 | |
| SCHEMBL24179519 | 0.77 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3HTR2AADRB2 | |
| SCHEMBL8059750 | 0.77 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3HTR2AADRB2 | |
| SCHEMBL990336 | 0.77 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3HTR2AADRB2 | |
| SCHEMBL27987174 | 0.77 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3HTR2AADRB2 | |
| SCHEMBL22081089 | 0.75 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3HTR2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002830-A | Isocyanate reacted with imino- or enamine-functional compound; RIM; cured composite | ICI AMERICAS INC. (US) | 1991-03-26 | — | — | US | disclosed |