SCHEMBL9810997

SCHEMBL9810997

CCC(C(=O)O)C(CC)(C(O)=S)c1nc2ccccc2s1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
MAPT P10636 2/20 0.43
GAA P10253 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 6/20 0.41
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
CSNK1D P48730 2/20 0.40
NCS1 P62166 1/20 0.40
CASR P41180 3/20 0.40
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 2/20 0.39
HTT P42858 2/20 0.39
HPGD P15428 4/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9810995 0.91 CASR (0.40) KDM4EMAPTGAAMEN1KMT2A
SCHEMBL11017725 0.83 NPC1 (0.38) KMT2ASMN1; SMN2NPC1RAB9AHPGD
SCHEMBL9811109 0.82 NPC1 (0.39) KDM4EMAPTGAAMEN1KMT2A
SCHEMBL11019144 0.82 KMT2A (0.47) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL9811133 0.80 NPC1 (0.38) KDM4EMAPTGAAMEN1KMT2A
SCHEMBL9811006 0.80 NPC1 (0.38) KDM4EMAPTGAAMEN1KMT2A
SCHEMBL9811146 0.80 HPGD (0.42) KDM4EMAPTGAAMEN1KMT2A
SCHEMBL9811099 0.78 ALDH1A1 (0.38) KDM4EMAPTGAAMEN1KMT2A
SCHEMBL11017724 0.77 NPC1 (0.38) KMT2ASMN1; SMN2NPC1RAB9AHPGD
SCHEMBL28565003 0.76 CASR (0.47) MAPTGAAMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0161219-B1 HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID ESTERS AND ANHYDRIDES AS CORROSION INHIBITING AGENTS CIBA-GEIGY AG (CH) 1991-06-12 EP disclosed
EP-0161219-A2 Heterocyclic mercaptocarboxylic-acid esters and anhydrides as corrosion inhibiting agents CIBA-GEIGY AG (CH) 1985-11-13 EP disclosed