Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811028 | 0.79 | MAPT (0.47) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL9443149 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9APIK3CAPIK3CB | |
| SCHEMBL9811022 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9APIK3CAPIK3CB | |
| SCHEMBL10645212 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9APPARAPPARG | |
| SCHEMBL10598891 | 0.72 | PIK3CA (0.48) | SMN1; SMN2NPC1RAB9APIK3CAPIK3CB | |
| SCHEMBL9811038 | 0.72 | MAPT (0.53) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL31421894 | 0.71 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9APIK3CAPIK3CB | |
| SCHEMBL10358304 | 0.69 | NPC1 (0.44) | SMN1; SMN2NPC1RAB9APIK3CAPIK3CB | |
| SCHEMBL30437919 | 0.66 | NPC1 (0.57) | SMN1; SMN2NPC1RAB9APIK3CAPIK3CB | |
| SCHEMBL6629030 | 0.66 | PIK3CA (0.61) | SMN1; SMN2NPC1RAB9APIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161219-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID ESTERS AND ANHYDRIDES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |