Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811031 | 0.80 | ALDH1A1 (0.49) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL10763711 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL10645212 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL9443149 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL9811210 | 0.77 | ALDH1A1 (0.50) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL10761935 | 0.77 | ALDH1A1 (0.52) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10759198 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL9811020 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL9811202 | 0.74 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL10756331 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161219-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID ESTERS AND ANHYDRIDES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |