SCHEMBL9811046

SCHEMBL9811046

CCc1ccccc1[SiH3].Cc1ccccc1[SiH3]

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.40
TAAR1 Q96RJ0 1/20 0.40
GABRA1 P14867 2/20 0.39
GABRB2 P47870 2/20 0.39
TSHR P16473 1/20 0.39
ACHE P22303 1/20 0.39
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PTGS1 P23219 1/20 0.38
SHBG P04278 1/20 0.38
KMT2A Q03164 1/20 0.37
MGLL Q99685 1/20 0.36
MAOB P27338 1/20 0.36
NLRP3 Q96P20 1/20 0.36
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88662 0.88
Hydrochloric Acid SCHEMBL27502087 0.85 GABRA1 (0.46) GABRA1GABRB2TSHRMAPTNPSR1
Fluoride SCHEMBL27930947 0.85 GABRA1 (0.46) GABRA1GABRB2TSHRMAPTNPSR1
SCHEMBL67969 0.83
Hydrochloric Acid SCHEMBL28959607 0.80 TSHR (0.53) TAAR1TSHRACHEMAPTALDH1A1
O-Xylene SCHEMBL28187928 0.78 TSHR (0.59) PTGS2TAAR1GABRA1GABRB2TSHR
SCHEMBL5489439 0.78 TAAR1 (0.54) PTGS2TAAR1GABRA1GABRB2TSHR
SCHEMBL29458957 0.78
SCHEMBL40576 0.78
SCHEMBL28021316 0.76 GABRA1 (0.38) GABRA1GABRB2TSHRMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5047569-A POLYMERIZING MONOMERIC OR PRECURSOR IN PRESENCE OF A DIPHOSPHOROUS NICKEL CHLORIDE CATALYSST ETHYL CORPORATION (US) 1991-09-10 US disclosed