Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306300 | 0.83 | HPGD (0.62) | HPGDCYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL9811094 | 0.81 | HPGD (0.60) | HPGDCSNK1DCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11585822 | 0.81 | HPGD (0.60) | HPGDCSNK1DCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2840140 | 0.79 | CSNK1D (0.60) | HPGDCSNK1DCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL718297 | 0.79 | HPGD (0.57) | HPGDCYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL900511 | 0.78 | HPGD (1.00) | HPGDCSNK1DCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5851278 | 0.78 | HPGD (0.69) | HPGDCSNK1DCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9306307 | 0.77 | HPGD (0.58) | HPGDCSNK1DCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10857871 | 0.76 | HPGD (0.67) | HPGDCSNK1DCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL717958 | 0.75 | HPGD (0.53) | HPGDCYP1A2CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161219-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID ESTERS AND ANHYDRIDES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |
| EP-0161219-A2 | Heterocyclic mercaptocarboxylic-acid esters and anhydrides as corrosion inhibiting agents | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |