Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10760409 | 0.78 | SMN1; SMN2 (0.45) | POLBSMN1; SMN2RECQLNPC1RAB9A | |
| SCHEMBL10760917 | 0.75 | ALDH1A1 (0.49) | POLBHPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9305867 | 0.75 | MAPT (0.50) | POLBHPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9811038 | 0.73 | MAPT (0.53) | POLBHPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10760482 | 0.72 | ALDH1A1 (0.49) | POLBHPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10763180 | 0.72 | ALDH1A1 (0.49) | POLBHPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10755766 | 0.71 | HPGD (0.58) | POLBHPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10760769 | 0.71 | SMN1; SMN2 (0.50) | POLBHPGDALDH1A1MAPTELANE | |
| SCHEMBL10759425 | 0.71 | MAPT (0.56) | POLBHPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9811212 | 0.71 | ALDH1A1 (0.46) | POLBHPGDALDH1A1MAPTELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161219-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID ESTERS AND ANHYDRIDES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |
| US-4696763-A | PAINTS, BLENDS | CIBA-GEIGY CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |