SCHEMBL9811233

SCHEMBL9811233

CCCC(Sc1nc2cc(C(=O)O)ccc2s1)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 18/20 0.74
PTGES O14684 1/20 0.57
ALOX5 P09917 1/20 0.57
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
PPARG P37231 4/20 0.52
PPARD Q03181 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8972964 0.86 PPARA (0.56) PPARAPTGESALOX5NPC1RAB9A
SCHEMBL14156095 0.82 PPARA (0.72) PPARANPC1RAB9ASMN1; SMN2
SCHEMBL9811162 0.81 PPARA (0.59) PPARAPPARGPPARD
SCHEMBL9306357 0.79 SMN1; SMN2 (0.54) PPARANPC1RAB9ASMN1; SMN2
SCHEMBL9306249 0.78 PPARA (0.54) PPARAPTGESALOX5NPC1RAB9A
SCHEMBL9443213 0.78 PPARA (0.54) PPARAPTGESALOX5PPARGPPARD
SCHEMBL9443367 0.77 PPARA (0.54) PPARAPTGESALOX5NPC1RAB9A
SCHEMBL14501813 0.77 SMN1; SMN2 (0.66) PPARANPC1RAB9ASMN1; SMN2
SCHEMBL9443185 0.77 PPARA (0.54) PPARAPTGESALOX5PPARGPPARD
SCHEMBL7034394 0.77 PPARA (0.62) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0161219-B1 HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID ESTERS AND ANHYDRIDES AS CORROSION INHIBITING AGENTS CIBA-GEIGY AG (CH) 1991-06-12 EP disclosed
EP-0161219-A2 Heterocyclic mercaptocarboxylic-acid esters and anhydrides as corrosion inhibiting agents CIBA-GEIGY AG (CH) 1985-11-13 EP disclosed