Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811162 | 0.86 | PPARA (0.59) | PPARAPPARG | |
| SCHEMBL8972964 | 0.85 | PPARA (0.56) | PPARANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9443367 | 0.83 | PPARA (0.54) | PPARANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8972533 | 0.83 | PPARA (0.59) | PPARAALDH1A1MAPT | |
| SCHEMBL9443213 | 0.83 | PPARA (0.54) | PPARAALDH1A1PTGESALOX5HPGD | |
| SCHEMBL9443185 | 0.83 | PPARA (0.54) | PPARAPTGESALOX5PPARG | |
| SCHEMBL9304890 | 0.80 | PPARA (0.71) | PPARANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10641479 | 0.79 | LMNA (0.46) | PPARANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10641498 | 0.79 | PPARA (0.43) | PPARANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL757236 | 0.78 | PPARA (0.76) | PPARASMN1; SMN2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |