Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10761762 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2POLBAPEX1 | |
| SCHEMBL10598608 | 0.85 | APEX1 (0.56) | ALDH1A1HPGDSMN1; SMN2POLBAPEX1 | |
| SCHEMBL9811041 | 0.85 | ALDH1A1 (0.54) | ALDH1A1HPGDSMN1; SMN2POLBAPEX1 | |
| Zinc Ion SCHEMBL9811248 | 0.83 | MAPK1 (0.50) | ALDH1A1HPGDSMN1; SMN2POLBAPEX1 | |
| SCHEMBL10762251 | 0.83 | APEX1 (0.56) | ALDH1A1HPGDSMN1; SMN2POLBAPEX1 | |
| SCHEMBL10892014 | 0.83 | APEX1 (0.56) | ALDH1A1HPGDSMN1; SMN2POLBAPEX1 | |
| Zinc Ion SCHEMBL10892436 | 0.83 | APEX1 (0.56) | ALDH1A1HPGDSMN1; SMN2POLBAPEX1 | |
| SCHEMBL10598582 | 0.83 | APEX1 (0.56) | ALDH1A1HPGDSMN1; SMN2POLBAPEX1 | |
| Potassium Ion SCHEMBL10897421 | 0.83 | APEX1 (0.56) | ALDH1A1HPGDSMN1; SMN2POLBAPEX1 | |
| SCHEMBL9811015 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HPGDSMN1; SMN2POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161219-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID ESTERS AND ANHYDRIDES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |
| US-4696763-A | PAINTS, BLENDS | CIBA-GEIGY CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |