⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27287218 | 0.85 | — | — | |
| SCHEMBL12799428 | 0.83 | MEN1 (0.78) | — | |
| SCHEMBL3074569 | 0.80 | — | — | |
| SCHEMBL11538335 | 0.80 | — | — | |
| SCHEMBL165731 | 0.78 | — | — | |
| SCHEMBL10101148 | 0.78 | MEN1 (0.89) | — | |
| SCHEMBL11460290 | 0.78 | — | — | |
| SCHEMBL17229157 | 0.78 | MEN1 (1.00) | — | |
| SCHEMBL11677298 | 0.76 | — | — | |
| SCHEMBL9259257 | 0.76 | MEN1 (0.94) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605329-B | Substituted indazole carboxamides or substituted azaindazole carboxamides FLT3 inhibitors and uses thereof | 河南中医药大学 | 2024-01-26 | — | — | CN | disclosed |
| WO-2023144228-A1 | AZIDE-FUNCTIONALIZED COPOLYMERS | SUSOS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| CN-114605329-A | Substituted indazole carboxamide or substituted azaindazole carboxamide FLT3 inhibitors and uses thereof | 河南中医药大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-1501917-A | Compounds useful as insecticides, compounds useful as acaricides, and processes to use and make same | 美国陶氏益农公司 | 2004-06-02 | — | — | CN | disclosed |
| EP-0223124-B1 | SUBSTITUTED AMINOSULFONYL 6-NITROBENZOIC-ESTERS OR AMIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4731369-A | Amides and esters of 2-(N-(hydroxypiperidinoalkyl) and (hydroxypyrrolidinoalkyl)-aminosulfonyl)-6-nitrobenzoic acids useful as adjuncts to radiation therapy | MERCK & CO. INC. (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0223124-A1 | Substituted aminosulfonyl 6-nitrobenzoic-esters or amides, processes for their preparation and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1987-05-27 | — | — | EP | disclosed |