Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.56 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768161 | 1.00 | RNASE1 (0.56) | RNASE1TYMSTERTCA12CA1 | |
| SCHEMBL9633553 | 0.92 | RNASE1 (0.57) | RNASE1TYMSTERTCA12CA1 | |
| SCHEMBL9811642 | 0.90 | RNASE1 (0.59) | RNASE1TYMSTERTCA12CA1 | |
| SCHEMBL8949961 | 0.89 | RNASE1 (0.55) | RNASE1TYMSTERTCA12CA1 | |
| SCHEMBL9331377 | 0.89 | RNASE1 (0.44) | RNASE1TYMSTERTCA12CA1 | |
| SCHEMBL9476925 | 0.89 | RNASE1 (0.44) | RNASE1TYMSTERTCA12CA1 | |
| Trifluoroacetic Acid SCHEMBL9359281 | 0.85 | RNASE1 (0.52) | RNASE1TYMSTERTCA12CA1 | |
| SCHEMBL30698170 | 0.85 | RNASE1 (0.61) | RNASE1TYMSTERTCA12CA1 | |
| SCHEMBL6542150 | 0.85 | RNASE1 (0.61) | RNASE1TYMSTERTCA12CA1 | |
| SCHEMBL8950041 | 0.84 | RNASE1 (0.49) | RNASE1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0208550-B1 | ANTIVIRAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-05-22 | — | — | EP | disclosed |
| US-4863906-A | VIRICIDES, VARICELLA ZOSTER, CYTOMEGALOVIRUS | BURROUGHS WELLCOME CO. (US) | 1989-09-05 | — | — | US | disclosed |