Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494667 | 0.87 | TYMS (0.54) | TYMS | |
| SCHEMBL9811607 | 0.87 | TYMS (0.54) | TYMS | |
| SCHEMBL9811636 | 0.82 | TYMS (0.57) | TYMS | |
| SCHEMBL9811641 | 0.82 | TYMS (0.57) | TYMS | |
| SCHEMBL9811615 | 0.82 | TYMS (0.46) | TYMS | |
| SCHEMBL10763077 | 0.82 | TYMS (0.46) | TYMS | |
| SCHEMBL9811622 | 0.82 | TYMS (0.48) | TYMS | |
| SCHEMBL9811616 | 0.82 | TYMS (0.48) | TYMS | |
| SCHEMBL14388455 | 0.81 | POLB (0.54) | BCHEPOLB | |
| SCHEMBL9811603 | 0.81 | LMNA (0.49) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0208550-B1 | ANTIVIRAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-05-22 | — | — | EP | disclosed |
| US-4863906-A | VIRICIDES, VARICELLA ZOSTER, CYTOMEGALOVIRUS | BURROUGHS WELLCOME CO. (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0208550-A2 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-01-14 | — | — | EP | disclosed |