SCHEMBL9811730

SCHEMBL9811730

CC(C)(C)OC(=O)CSNC(=O)NSCC(=O)OC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 1/20 0.37
CCNE2 O96020 1/20 0.37
CDK1 P06493 1/20 0.37
CDK4 P11802 1/20 0.37
CCNB1 P14635 1/20 0.37
CCND1 P24385 1/20 0.37
CCNE1 P24864 1/20 0.37
CDK2 P24941 1/20 0.37
CCNB3 Q8WWL7 1/20 0.37
DGAT1 O75907 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HTT P42858 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10274076 0.76 CA12 (0.45) DGAT1CYP2D6CYP1A2CYP2C9CYP2C19
SCHEMBL9784220 0.73 CCNB2 (0.37) CCNB2CCNE2CDK1CDK4CCNB1
SCHEMBL29080281 0.73 CCNB2 (0.37) CCNB2CCNE2CDK1CDK4CCNB1
SCHEMBL1845681 0.72 HTT (0.41) CCNB2CCNE2CDK1CDK4CCNB1
SCHEMBL7876571 0.72 CYP2D6 (0.36) CCNB2CCNE2CDK1CDK4CCNB1
SCHEMBL7876569 0.72 CYP2D6 (0.36) CCNB2CCNE2CDK1CDK4CCNB1
SCHEMBL241533 0.71 DGAT1 (0.46) DGAT1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL8843809 0.71 CCNB2 (0.36) CCNB2CCNE2CDK1CDK4CCNB1
SCHEMBL19403452 0.71 CCNB2 (0.36) CCNB2CCNE2CDK1CDK4CCNB1
SCHEMBL17119183 0.70 HDAC3 (0.39) CCNB2CCNE2CDK1CDK4CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5064861-A ACYLATED AMINE COMPOUNDS WHICH ARE USEFUL FUNGICIGAL AGENTS ROUSSEL UCLAF (FR) 1991-11-12 US disclosed