⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812100 | 0.92 | — | — | |
| SCHEMBL79345 | 0.77 | NOS2 (0.33) | — | |
| SCHEMBL1145721 | 0.72 | — | — | |
| SCHEMBL15803200 | 0.72 | — | — | |
| SCHEMBL300796 | 0.72 | — | — | |
| SCHEMBL694827 | 0.72 | — | — | |
| SCHEMBL4260336 | 0.72 | MEN1 (0.33) | — | |
| SCHEMBL6295816 | 0.72 | — | — | |
| SCHEMBL22882412 | 0.72 | — | — | |
| SCHEMBL20408823 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224208-B1 | TETRAENYL PROSTAGLANDINS | G.D. Searle & Co. (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4863961-A | ANTISECRETORY AND CYTOPROTECTIVE AGENTS | G. D. SEARLE & CO. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4847293-A | ANTIULCER AGENTS | G. D. SEARLE & CO. (US) | 1989-07-11 | — | — | US | disclosed |
| US-4820728-A | ANTISECRETORY AGENTS | G. D. SEARLE & CO. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0142158-B1 | OMEGA-CYCLOALKYL PROSTAGLANDINS | G.D. Searle & Co. (US) | 1988-12-28 | — | — | EP | disclosed |
| US-4754059-A | ANTISECRETORY AGENT WITH REDUCED DIARRHEA SIDE EFFECT | G. D. SEARLE & CO. (US) | 1988-06-28 | — | — | US | disclosed |
| US-4713477-A | ANTISECRETORY AGENTS | G. D. SEARLE & CO. (US) | 1987-12-15 | — | — | US | disclosed |
| US-4683328-A | Tetraenyl prostaglandins | G. D. SEARLE & CO. (US) | 1987-07-28 | — | — | US | disclosed |
| EP-0224208-A2 | Tetraenyl prostaglandins | G.D. Searle & Co. (US) | 1987-06-03 | — | — | EP | disclosed |
| EP-0142158-A2 | Omega-cycloalkyl prostaglandins | G.D. Searle & Co. (US) | 1985-05-22 | — | — | EP | disclosed |
| US-4499296-A | ANTISECRETORY AND ANTIULCER AGENTS; GLANDULAR AND LIVER DISORDERS | G. D. SEARLE & CO. (US) | 1985-02-12 | — | — | US | disclosed |
| US-3965143-A | 16-Oxygenated prostanoic acid derivatives | G. D. SEARLE & CO. (US) | 1976-06-22 | — | — | US | disclosed |