Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812395 | 1.00 | CYP11B1 (0.40) | CYP11B1CYP11B2MAOAMAOBUSP5 | |
| SCHEMBL9812513 | 0.92 | HIF1A (0.37) | USP5HDAC6NPC1MAPTCASP3 | |
| SCHEMBL9812501 | 0.92 | HIF1A (0.37) | USP5HDAC6NPC1MAPTCASP3 | |
| SCHEMBL9812514 | 0.91 | HIF1A (0.41) | MAOBNPC1RAB9A | |
| SCHEMBL9812523 | 0.91 | HIF1A (0.41) | MAOBNPC1RAB9A | |
| SCHEMBL9812485 | 0.90 | SCN9A (0.37) | NPC1MAPTCASP3RAB9ASMN1; SMN2 | |
| SCHEMBL9812491 | 0.90 | SCN9A (0.37) | NPC1MAPTCASP3RAB9ASMN1; SMN2 | |
| SCHEMBL10484281 | 0.89 | KMT2A (0.39) | USP5HDAC6NPC1MAPTCASP3 | |
| SCHEMBL10484276 | 0.89 | KMT2A (0.39) | USP5HDAC6NPC1MAPTCASP3 | |
| SCHEMBL9812497 | 0.88 | MAOB (0.38) | MAOBNPC1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219975-B1 | FLUOROPHENYLCYCLOHEXANE DERIVATIVE | Chisso Corporation (JP) | 1991-07-03 | — | — | EP | disclosed |
| EP-0219975-A1 | Fluorophenylcyclohexane derivative | Chisso Corporation (JP) | 1987-04-29 | — | — | EP | disclosed |