Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10484276 | 1.00 | KMT2A (0.39) | KMT2AALDH1A1CYP1A2CYP2C19HPGD | |
| SCHEMBL9812523 | 0.91 | HIF1A (0.41) | KMT2AALDH1A1HPGDALOX15RAB9A | |
| SCHEMBL9812514 | 0.91 | HIF1A (0.41) | KMT2AALDH1A1HPGDALOX15RAB9A | |
| SCHEMBL9812515 | 0.90 | HIF1A (0.39) | KMT2ACYP1A2CYP2C19RAB9AMAPT | |
| SCHEMBL9812529 | 0.90 | HIF1A (0.39) | KMT2ACYP1A2CYP2C19RAB9AMAPT | |
| SCHEMBL9812404 | 0.89 | CYP11B1 (0.40) | RAB9ACASP3SENP8SENP7SENP6 | |
| SCHEMBL9812395 | 0.89 | CYP11B1 (0.40) | RAB9ACASP3SENP8SENP7SENP6 | |
| SCHEMBL9812497 | 0.88 | MAOB (0.38) | KMT2ACYP1A2CYP2C19HPGDRAB9A | |
| SCHEMBL9812509 | 0.88 | MAOB (0.38) | KMT2ACYP1A2CYP2C19HPGDRAB9A | |
| SCHEMBL9812411 | 0.88 | HIF1A (0.39) | KMT2AALDH1A1CYP1A2CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4855076-A | Fluorophenylcyclohexane derivative | CHISSO CORPORATION (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0219975-A1 | Fluorophenylcyclohexane derivative | Chisso Corporation (JP) | 1987-04-29 | — | — | EP | disclosed |