Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16775234 | 0.75 | KMT2A (0.70) | KMT2AMAPK1LMNAALDH1A1TSHR | |
| SCHEMBL16759895 | 0.75 | KMT2A (0.70) | KMT2AMAPK1LMNAALDH1A1TSHR | |
| SCHEMBL7825065 | 0.74 | MEN1 (0.70) | KMT2AMAPK1LMNAALDH1A1TSHR | |
| SCHEMBL24481551 | 0.70 | KMT2A (0.63) | KMT2AMAPK1LMNAALDH1A1TSHR | |
| SCHEMBL18517357 | 0.70 | MEN1 (0.54) | KMT2ALMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL19971697 | 0.70 | MEN1 (0.54) | KMT2ALMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL19971698 | 0.70 | MEN1 (0.54) | KMT2ALMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9975770 | 0.68 | KMT2A (0.66) | KMT2ALMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10031595 | 0.68 | KMT2A (0.66) | KMT2ALMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8362397 | 0.66 | ALDH1A1 (0.58) | KMT2AMAPK1LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049564-A | Hypotensive, 5-hydroxytryptamine | ABBOTT LABORATORIES (US) | 1991-09-17 | — | — | US | disclosed |