Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812547 | 1.00 | CYP2C9 (0.39) | CYP2C9ALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL7736458 | 0.89 | CYP2C9 (0.52) | CYP2C9ALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL7736461 | 0.89 | CYP2C9 (0.52) | CYP2C9ALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL14268568 | 0.87 | ACMSD (0.43) | CYP2C9ALDH1A1LMNAMAPTACMSD | |
| SCHEMBL9669086 | 0.86 | CYP2C9 (0.43) | CYP2C9ALDH1A1LMNAMAPTCYP3A4 | |
| SCHEMBL7736041 | 0.84 | ACMSD (0.40) | CYP2C9ALDH1A1LMNAMAPTACMSD | |
| SCHEMBL7736045 | 0.84 | ACMSD (0.40) | CYP2C9ALDH1A1LMNAMAPTACMSD | |
| SCHEMBL7736038 | 0.84 | ACMSD (0.40) | CYP2C9ALDH1A1LMNAMAPTACMSD | |
| SCHEMBL7736043 | 0.84 | ACMSD (0.40) | CYP2C9ALDH1A1LMNAMAPTACMSD | |
| SCHEMBL9327947 | 0.83 | BTK (0.38) | CYP2C9ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219975-B1 | FLUOROPHENYLCYCLOHEXANE DERIVATIVE | Chisso Corporation (JP) | 1991-07-03 | — | — | EP | disclosed |
| US-4855076-A | Fluorophenylcyclohexane derivative | CHISSO CORPORATION (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0219975-A1 | Fluorophenylcyclohexane derivative | Chisso Corporation (JP) | 1987-04-29 | — | — | EP | disclosed |