Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 6/20 | 0.30 |
| ▸ | RAB9A | P51151 | 6/20 | 0.30 |
| ▸ | HTT | P42858 | 4/20 | 0.30 |
| ▸ | GALR3 | O60755 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27836614 | 1.00 | PTGS1 (0.36) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL9812701 | 1.00 | PTGS1 (0.36) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL9812725 | 0.93 | GRM2 (0.35) | GRM2 | |
| Water SCHEMBL28757012 | 0.92 | GRM2 (0.34) | GRM2 | |
| Hydrochloric Acid SCHEMBL28009755 | 0.92 | GRM2 (0.34) | GRM2 | |
| SCHEMBL27703879 | 0.86 | — | — | |
| SCHEMBL11291370 | 0.80 | PTGS1 (0.40) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL5795034 | 0.79 | — | — | |
| SCHEMBL27696873 | 0.78 | MGLL (0.39) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL27683092 | 0.78 | MGLL (0.39) | PTGS1PTGS2MGLLFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933469-A | Method for preparing oxybisphthalimides | GENERAL ELECTRIC COMPANY (US) | 1990-06-12 | — | — | US | claimed |
| EP-0126950-B1 | METHOD FOR MAKING AROMATIC ETHERS AND CATALYST USED IN SUCH METHOD | GENERAL ELECTRIC COMPANY (US) | 1991-07-31 | — | — | EP | disclosed |
| US-4933469-A | Method for preparing oxybisphthalimides | GENERAL ELECTRIC COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| US-4605745-A | PHASE TRANSFER CATALYSTS; AROMATIC ETHERS IN IMPROVED YIELDS | GENERAL ELECTRIC COMPANY (US) | 1986-08-12 | — | — | US | disclosed |
| US-4513141-A | BY DISPLACING REACTIVE RADICALS ON AROMATIC NUCLEUS | GENERAL ELECTRIC COMPANY (US) | 1985-04-23 | — | — | US | disclosed |
| EP-0126950-A2 | Method for making aromatic ethers and catalyst used in such method | GENERAL ELECTRIC COMPANY (US) | 1984-12-05 | — | — | EP | disclosed |