Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.60 |
| ▸ | PLAU | P00749 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.52 |
| ▸ | KLK1 | P06870 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | JAK1 | P23458 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812748 | 0.91 | HDAC2 (0.60) | HDAC2HDAC1HDAC3NCOR2PLAU | |
| SCHEMBL2949633 | 0.83 | HDAC2 (0.63) | HDAC2HDAC1HDAC3NCOR2PLAU | |
| SCHEMBL29364540 | 0.83 | HDAC2 (0.63) | HDAC2HDAC1HDAC3NCOR2PLAU | |
| SCHEMBL27498643 | 0.81 | HDAC2 (0.59) | HDAC2HDAC1HDAC3NCOR2PLAU | |
| SCHEMBL9185611 | 0.80 | TTR (0.56) | ALDH1A1LMNAPOLBKMT2AMAPT | |
| SCHEMBL11701111 | 0.79 | HDAC2 (0.58) | HDAC2HDAC1HDAC3NCOR2PLAU | |
| SCHEMBL9116112 | 0.79 | HDAC2 (0.58) | HDAC2HDAC1HDAC3NCOR2PLAU | |
| SCHEMBL17267862 | 0.79 | ALOX15 (0.49) | HDAC2HDAC1HDAC3NCOR2PLAU | |
| SCHEMBL11200897 | 0.78 | HDAC2 (0.59) | HDAC2HDAC1HDAC3NCOR2PLAU | |
| SCHEMBL17267852 | 0.77 | ALOX15 (0.48) | PKMPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261575-B1 | SOLVENT RESISTANT POLYETHERAMIDEIMIDES | GENERAL ELECTRIC COMPANY (US) | 1991-07-31 | — | — | EP | claimed |
| US-4742150-A | INJECTION MOLDABLE THERMOPLASTIC | GENERAL ELECTRIC COMPANY (US) | 1988-05-03 | — | — | US | claimed |
| EP-0261575-A1 | Solvent resistant polyetheramideimides | GENERAL ELECTRIC COMPANY (US) | 1988-03-30 | — | — | EP | claimed |
| EP-0261575-B1 | SOLVENT RESISTANT POLYETHERAMIDEIMIDES | GENERAL ELECTRIC COMPANY (US) | 1991-07-31 | — | — | EP | disclosed |
| US-4742150-A | INJECTION MOLDABLE THERMOPLASTIC | GENERAL ELECTRIC COMPANY (US) | 1988-05-03 | — | — | US | disclosed |
| EP-0261575-A1 | Solvent resistant polyetheramideimides | GENERAL ELECTRIC COMPANY (US) | 1988-03-30 | — | — | EP | disclosed |