Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | USP2 | O75604 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fosfonet SCHEMBL9706163 | 1.00 | TOP2A (0.49) | TOP2APOLBGAANPC1RAD52 | |
| Foscarnet SCHEMBL9706150 | 0.91 | TOP2A (0.52) | TOP2APOLBGAANPC1RAD52 | |
| SCHEMBL30297107 | 0.86 | POLB (0.61) | TOP2APOLBGAANPC1RAD52 | |
| SCHEMBL1581068 | 0.86 | POLB (0.61) | TOP2APOLBGAANPC1RAD52 | |
| SCHEMBL9706159 | 0.83 | TOP2A (0.43) | TOP2APOLBGAANPC1RAD52 | |
| SCHEMBL9706146 | 0.79 | TOP2A (0.44) | TOP2APOLBGAANPC1RAD52 | |
| SCHEMBL9706276 | 0.77 | POLB (0.75) | TOP2APOLBGAANPC1RAD52 | |
| SCHEMBL9706078 | 0.77 | POLB (0.60) | TOP2APOLBGAANPC1RAD52 | |
| SCHEMBL1232971 | 0.74 | WEE1 (0.44) | TOP2APOLBGAANPC1RAD52 | |
| SCHEMBL30297105 | 0.74 | WEE1 (0.44) | TOP2APOLBGAANPC1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990510-A | Viricides, anticancer agents | LEIF LUNDBLAD (BE) | 1991-02-05 | — | — | US | disclosed |