Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413309 | 0.83 | GAA (0.55) | GAAHTTMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10899727 | 0.82 | GAA (0.71) | GAAHTTMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9813043 | 0.80 | GAA (0.52) | GAAHTTMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL16884075 | 0.72 | KDM4E (0.67) | GAAHTTMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL21957070 | 0.71 | HTT (0.67) | GAAHTTMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9815602 | 0.71 | MEN1 (0.46) | GAAHTTKDM4EALDH1A1MAPK1 | |
| SCHEMBL4145433 | 0.71 | HTT (0.66) | HTTMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL5784912 | 0.71 | HTT (0.55) | GAAHTTMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL16883438 | 0.69 | HTT (0.56) | GAAHTTMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7370799 | 0.69 | KDM4E (0.54) | GAAHTTMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266549-B1 | CINNAMYL AMINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-06-19 | — | — | EP | disclosed |