Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PDE5A | O76074 | 4/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813156 | 1.00 | LMNA (0.42) | LMNAMAPTGAANPC1RAB9A | |
| SCHEMBL10746902 | 0.90 | MAPT (0.42) | LMNAMAPTGAANPC1RAB9A | |
| SCHEMBL6051347 | 0.90 | MAPT (0.42) | LMNAMAPTGAANPC1RAB9A | |
| SCHEMBL6051352 | 0.90 | MAPT (0.42) | LMNAMAPTGAANPC1RAB9A | |
| SCHEMBL8843794 | 0.90 | GAA (0.39) | LMNAMAPTGAANPC1RAB9A | |
| SCHEMBL8843790 | 0.90 | GAA (0.39) | LMNAMAPTGAANPC1RAB9A | |
| SCHEMBL9021727 | 0.88 | MAPT (0.44) | LMNAMAPTGAANPC1RAB9A | |
| SCHEMBL9021733 | 0.88 | MAPT (0.44) | LMNAMAPTGAANPC1RAB9A | |
| SCHEMBL8527292 | 0.87 | MAPT (0.46) | LMNAMAPTGAANPC1RAB9A | |
| SCHEMBL7774067 | 0.87 | MAPT (0.43) | LMNAMAPTGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153709-B1 | NOVEL CEPHALOSPORIN DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4845211-A | Amino-3-substituted-methyl-3-cephem-4-carboxylic acid and lower alkylsilyl derivatives thereof | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4785090-A | ANTIBIOTICS, BACTERICIDES | MEIJI SEIKA KAISHA, LTD. (JP) | 1988-11-15 | — | — | US | disclosed |
| US-4699980-A | Process for preparing 3-substituted-methyl-3-cephem derivatives | YAMANOUCHI PHARMACUTICAL CO., LTD. (JP) | 1987-10-13 | — | — | US | disclosed |
| US-4690921-A | BACTERICIDES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1987-09-01 | — | — | US | disclosed |
| US-4608373-A | BACTERICIDES, ANTIBIOTICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-08-26 | — | — | US | disclosed |
| EP-0154417-A2 | 7-Amino-3-substituted-methyl-3-cephem-4-carboxylic acid and lower alkylsilyl derivatives thereof, and their production | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1985-09-11 | — | — | EP | disclosed |
| EP-0153709-A2 | Novel cephalosporin derivatives | MEIJI SEIKA KAISHA LTD. (JP) | 1985-09-04 | — | — | EP | disclosed |
| EP-0142274-A2 | Cephalosporin compounds and salts thereof, their production, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1985-05-22 | — | — | EP | disclosed |
| EP-0112164-A2 | Cephem compounds, and their production, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-06-27 | — | — | EP | disclosed |