Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813293 | 0.86 | TSHR (0.43) | ADORA3PRKD3MAPK8TSHRMAPK1 | |
| SCHEMBL19699541 | 0.85 | RIOK2 (0.46) | TSHRMAPK1PDE3BPDE3AP2RY12 | |
| SCHEMBL19699543 | 0.85 | RIOK2 (0.46) | TSHRMAPK1PDE3BPDE3AP2RY12 | |
| SCHEMBL19728701 | 0.84 | TSHR (0.38) | ADORA3PRKD3MAPK8MAPK9TSHR | |
| SCHEMBL19728700 | 0.84 | TSHR (0.38) | ADORA3PRKD3MAPK8MAPK9TSHR | |
| SCHEMBL19699559 | 0.81 | ALDH1A1 (0.50) | TSHRMAPK1MAPTALDH1A1KMT2A | |
| SCHEMBL19699547 | 0.81 | ALDH1A1 (0.50) | TSHRMAPK1MAPTALDH1A1KMT2A | |
| SCHEMBL9813335 | 0.79 | MAPK8 (0.45) | ADORA3MAPK8MAPK9TSHRMAPK1 | |
| SCHEMBL19699602 | 0.79 | TSHR (0.39) | TSHRMAPK1ADORA1PDE3BPDE3A | |
| SCHEMBL19699611 | 0.79 | TSHR (0.39) | TSHRMAPK1ADORA1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434576-A1 | Thermotropic adducts from non-mesogenic species bound by hydrogen bonds and method for their preparation | RHONE-POULENC CHIMIE (FR) | 1991-06-26 | — | — | EP | disclosed |