SCHEMBL98134

SCHEMBL98134

Cc1ncnc2c1ncn2C1C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.75

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.75
PNP P00491 1/20 0.57
LMNA P02545 1/20 0.57
TP53 P04637 1/20 0.57
HTT P42858 1/20 0.57
PDE4D Q08499 1/20 0.57
PDE3A Q14432 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
RXFP1 Q9HBX9 1/20 0.57
PIM1 P11309 1/20 0.57
CSNK2A2 P19784 1/20 0.57
CSNK2B P67870 1/20 0.57
CSNK2A1 P68400 1/20 0.57
CSNK2A3 Q8NEV1 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2048956 1.00 HIF1A (0.75) HIF1APNPLMNATP53HTT
SCHEMBL23982423 1.00 HIF1A (0.75) HIF1APNPLMNATP53HTT
SCHEMBL17612282 1.00 HIF1A (0.75) HIF1APNPLMNATP53HTT
SCHEMBL2408903 1.00 HIF1A (0.75) HIF1APNPLMNATP53HTT
SCHEMBL14440926 0.92 HIF1A (0.64) HIF1ASMN1; SMN2
Deoxyinosine SCHEMBL2000526 0.86 HIF1A (0.73) HIF1APNPLMNATP53HTT
Deoxyinosine SCHEMBL324457 0.86 HIF1A (0.73) HIF1APNPLMNATP53HTT
Deoxyinosine SCHEMBL5982293 0.86 HIF1A (0.73) HIF1APNPLMNATP53HTT
Deoxyinosine SCHEMBL24307 0.86 HIF1A (0.73) HIF1APNPLMNATP53HTT
Deoxyinosine SCHEMBL7191121 0.86 HIF1A (0.73) HIF1APNPLMNATP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 492 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4388114-A1 CELL-TO-CELL DELIVERY OF RNA CIRCUITS California Institute of Technology (US) 2024-06-26 EP claimed
WO-2024124190-A1 ENGINEERED MICROORGANISMS FOR DELIVERY OF THERAPEUTIC AGENTS MICROBIAL MACHINES, INC. (US) 2024-06-13 WO claimed
EP-4370686-A1 STOICHIOMETRIC EXPRESSION OF MESSENGER POLYCISTRONS California Institute of Technology (US) 2024-05-22 EP claimed
WO-2024081912-A1 PROTEIN-BASED SIGNAL AMPLIFICATION CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2024-04-18 WO claimed
US-20240018513-A1 SYNTHETIC INTRONS FOR TARGETED GENE EXPRESSION FRED HUTCHINSON CANCER CENTER (US) 2024-01-18 US claimed
EP-4305179-A2 ACOUSTIC REMOTE CONTROL OF MICROBIAL IMMUNOTHERAPY California Institute of Technology (US) 2024-01-17 EP claimed
WO-2024011146-A1 A SYNTHETIC PROTEIN-LEVEL NEURAL NETWORK IN MAMMALIAN CELLS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2024-01-11 WO claimed
EP-4232577-A1 SYNTHETIC INTRONS FOR TARGETED GENE EXPRESSION Fred Hutchinson Cancer Center (US) 2023-08-30 EP claimed
WO-2023070134-A2 SYNTHETIC INTRONS FOR TARGETED GENE EXPRESSION FRED HUTCHINSON CANCER CENTER (US) 2023-04-27 WO claimed
US-20230103980-A1 THERMAL STATE SWITCHES IN MACROPHAGES CALIFORNIA INSTITUTE OF TECHNOLOGY 2023-04-06 US claimed
US-7820184-B2 Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders GENELUX CORPORATION (US) 2010-10-26 US claimed
US-7662398-B2 anticancer treatment by administering a recombinant vaccina virus of a modified TK thymidine kinase and hemagglutinin gene; virus does not accumulate to toxic levels in non-targeted organs; kits GENELUX CORPORATION (US) 2010-02-16 US claimed
US-7588771-B2 Microorganisms for therapy GENELUX CORPORATION (US) 2009-09-15 US claimed
US-20090180987-A1 Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders GENELUX CORPORATION 2009-07-16 US claimed
EP-2028270-A2 Modified recombinant vaccina viruses and uses thereof Genelux Corporation (US) 2009-02-25 EP claimed
EP-1644492-B1 MODIFIED RECOMBINANT VACCINIA VIRUSES, USES THEREOF GENELUX CORP (US) 2009-01-07 EP claimed
US-20070025981-A1 anticancer treatment by administering a recombinant vaccina virus of a modified TK thymidine kinase and hemagglutinin gene; virus does not accumulate to toxic levels in non-targeted organs; kits GENELUX CORPORATION 2007-02-01 US claimed
US-20060051370-A1 anticancer treatment by administering a recombinant vaccina virus of a modified TK thymidine kinase and HA hemagglutinin gene; virus does not accumulate to toxic levels in non-targeted organs GENELUX CORPORATION 2006-03-09 US claimed
US-5902740-A Process for the decontamination of cell cultures containing mycoplasmas BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1999-05-11 US claimed
US-4387161-A INCUBATION WITH 6-METHYLPURINE DEOXYRIBOSIDE; ANTIGROWTH AGENTS; CYTOLYSIS INSTITUTE FOR MEDICAL RESEARCH (US) 1983-06-07 US claimed