Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 4/20 | 0.49 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813501 | 0.92 | TDP1 (0.51) | TDP1ACACBAPPSIGMAR1MCHR1 | |
| SCHEMBL9813514 | 0.90 | TDP1 (0.50) | TDP1ACACBAPPSIGMAR1MCHR1 | |
| SCHEMBL9813495 | 0.90 | ACACB (0.50) | TDP1ACACBSIGMAR1PARP15PARP10 | |
| SCHEMBL9813523 | 0.88 | ACACB (0.49) | TDP1ACACBSIGMAR1PARP15PARP10 | |
| SCHEMBL9813522 | 0.88 | ACACB (0.50) | ACACBSIGMAR1PARP15PARP10PARP2 | |
| SCHEMBL9813490 | 0.88 | TDP1 (0.56) | TDP1ACACBAPPSIGMAR1MCHR1 | |
| SCHEMBL9813492 | 0.87 | ACACB (0.48) | TDP1ACACBSIGMAR1PARP15PARP10 | |
| SCHEMBL9813502 | 0.87 | ACACB (0.48) | ACACBSIGMAR1DRD2DRD4 | |
| SCHEMBL9813493 | 0.87 | ACACB (0.51) | ACACBSIGMAR1KDM1APARP15PARP10 | |
| SCHEMBL9813508 | 0.86 | ACACB (0.54) | ACACBSIGMAR1PARP15PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308747-B1 | TOLAN COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4895672-A | Tolan compound and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0308747-A2 | Tolan compound and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1989-03-29 | — | — | EP | disclosed |