Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813489 | 0.92 | ACACB (0.46) | ACACBCHRNB2CHRNA4SIGMAR1DRD2 | |
| SCHEMBL9813520 | 0.91 | ACACB (0.46) | ACACBCHRNB2CHRNA4SIGMAR1DRD2 | |
| SCHEMBL9813495 | 0.88 | ACACB (0.50) | ACACBSIGMAR1 | |
| SCHEMBL9813527 | 0.88 | ACACB (0.47) | ACACBCHRNB2CHRNA4SIGMAR1DRD2 | |
| SCHEMBL9813523 | 0.87 | ACACB (0.49) | ACACBSIGMAR1 | |
| SCHEMBL9813522 | 0.87 | ACACB (0.50) | ACACBSIGMAR1 | |
| SCHEMBL9813499 | 0.87 | TDP1 (0.54) | ACACBSIGMAR1DRD2DRD4 | |
| SCHEMBL9813492 | 0.86 | ACACB (0.48) | ACACBSIGMAR1 | |
| SCHEMBL9813493 | 0.86 | ACACB (0.51) | ACACBSIGMAR1 | |
| SCHEMBL9813515 | 0.84 | ACACB (0.47) | ACACBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308747-B1 | TOLAN COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4895672-A | Tolan compound and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0308747-A2 | Tolan compound and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1989-03-29 | — | — | EP | disclosed |