Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.52 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.52 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.52 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.52 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.52 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696314 | 0.87 | PPARA (0.69) | PPARAPPARGPLA2G4BTSHRPLA2G4A | |
| SCHEMBL4001417 | 0.87 | PPARA (0.69) | PPARAPPARGPLA2G4BTSHRPLA2G4A | |
| SCHEMBL5696298 | 0.87 | PPARA (0.69) | PPARAPPARGPLA2G4BTSHRPLA2G4A | |
| SCHEMBL446792 | 0.87 | PPARA (0.69) | PPARAPPARGPLA2G4BTSHRPLA2G4A | |
| SCHEMBL3997525 | 0.87 | PPARA (0.69) | PPARAPPARGPLA2G4BTSHRPLA2G4A | |
| SCHEMBL2054507 | 0.86 | PPARA (0.67) | PPARAPPARGPLA2G4BTSHRPLA2G4A | |
| SCHEMBL12611895 | 0.84 | ALDH1A1 (0.61) | PPARAPPARGPLA2G4BTSHRPTPN1 | |
| SCHEMBL9653716 | 0.83 | PPARA (0.64) | PPARAPPARGPLA2G4BTSHRPLA2G4A | |
| SCHEMBL11332214 | 0.83 | TBXA2R (0.58) | PPARAPPARGPLA2G4BPSEN1PSEN2 | |
| SCHEMBL11332902 | 0.83 | TBXA2R (0.58) | PPARAPPARGPLA2G4BPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301421-B1 | SULFUR COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |
| EP-0301421-A2 | Sulfur compounds, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1989-02-01 | — | — | EP | disclosed |