Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.64 |
| ▸ | PPARG | P37231 | 2/20 | 0.64 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA4 | P22748 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | PTGIR | P43119 | 2/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813851 | 0.96 | PPARA (0.62) | PPARAPPARGMGLLCA12CA1 | |
| SCHEMBL9813826 | 0.90 | PPARA (0.59) | PPARAPPARGMGLLCA12CA1 | |
| SCHEMBL9813750 | 0.90 | PPARA (0.59) | PPARAPPARGMGLLCA12CA1 | |
| SCHEMBL9813802 | 0.86 | PPARA (0.57) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL9813812 | 0.86 | PPARA (0.57) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL2769715 | 0.83 | PPARA (0.74) | PPARAPPARGPTGIRPTGDR2ALOX15 | |
| SCHEMBL8351512 | 0.83 | PPARA (0.59) | PPARAPPARGMGLLCA12CA1 | |
| SCHEMBL9813009 | 0.83 | TBXA2R (0.63) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL9812947 | 0.81 | TBXA2R (0.65) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL9813734 | 0.81 | TBXA2R (0.64) | PPARAMGLLPTGIRALOX15FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301421-B1 | SULFUR COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |
| EP-0301421-A2 | Sulfur compounds, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1989-02-01 | — | — | EP | disclosed |