Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.63 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.63 |
| ▸ | PPARA | Q07869 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SGMS1 | Q86VZ5 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | PTGIR | P43119 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812947 | 0.96 | TBXA2R (0.65) | TBXA2RTBXAS1PPARAPPARGALDH1A1 | |
| SCHEMBL9813017 | 0.92 | TBXA2R (0.75) | TBXA2RTBXAS1PPARAPPARGALDH1A1 | |
| SCHEMBL9813021 | 0.88 | ALDH1A1 (0.62) | TBXA2RTBXAS1PPARAPPARGALDH1A1 | |
| SCHEMBL9812933 | 0.87 | ALDH1A1 (0.61) | TBXA2RTBXAS1PPARAPPARGALDH1A1 | |
| SCHEMBL9813027 | 0.85 | TBXAS1 (0.51) | TBXA2RTBXAS1PPARAPPARGALDH1A1 | |
| SCHEMBL9812978 | 0.84 | TBXA2R (0.60) | TBXA2RTBXAS1PPARAPPARGALDH1A1 | |
| SCHEMBL9617068 | 0.83 | SGMS1 (0.63) | TBXA2RTBXAS1ALDH1A1AKR1C3LMNA | |
| SCHEMBL11358325 | 0.83 | TBXA2R (0.85) | TBXA2RTBXAS1ALDH1A1TDP1SGMS1 | |
| SCHEMBL9813784 | 0.83 | PPARA (0.64) | TBXA2RTBXAS1PPARAPPARGLMNA | |
| SCHEMBL9127503 | 0.83 | TBXA2R (0.69) | TBXA2RTBXAS1AKR1C3SGMS1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223593-B1 | PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION | GLAXO GROUP LIMITED (GB) | 1991-08-07 | — | — | EP | disclosed |
| EP-0223593-A2 | Phenoxyalkylcarboxylic acids and esters and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1987-05-27 | — | — | EP | disclosed |