Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175094 | 0.72 | TLR4 (0.50) | TLR4 | |
| SCHEMBL11443954 | 0.71 | TLR4 (0.58) | TLR4 | |
| SCHEMBL28617732 | 0.69 | — | — | |
| SCHEMBL10772651 | 0.67 | TLR4 (0.34) | TLR4 | |
| SCHEMBL8874668 | 0.64 | TLR4 (0.55) | TLR4 | |
| SCHEMBL15661377 | 0.63 | TLR4 (0.33) | TLR4 | |
| SCHEMBL11205 | 0.63 | MAPT (0.30) | — | |
| SCHEMBL1964176 | 0.63 | TLR4 (0.48) | TLR4 | |
| SCHEMBL7369844 | 0.62 | — | — | |
| SCHEMBL30130600 | 0.62 | TLR4 (0.56) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219199-B1 | METHOD FOR PREPARATION OF LACTONES | COULSTON INTERNATIONAL CORPORATION (US) | 1991-07-31 | — | — | EP | disclosed |